Coffee revealed to have unexpected benefits for liver and kidneys

Regular coffee consumption can reduce the risk of liver and kidney diseases due to biologically active metabolites that form after the drink is processed in the body.

As reported by BAKU.WS with reference to "Gazeta.Ru", Chinese researchers analyzed data from previously published works and found out which coffee components actually enter the bloodstream, how they are processed by the gut microbiota, and which of the resulting compounds have pronounced biological effects. It turned out that the key role is played not by caffeine itself or the original molecules of the drink, but by metabolites of chlorogenic acids, diterpenes, and other substances that have strong anti-inflammatory and antioxidant properties.

Systematic data from large cohort and clinical studies show that regular coffee consumption is associated with a lower risk of cirrhosis, hepatocellular carcinoma, non-alcoholic fatty liver disease, and chronic kidney diseases. The protective effect is determined precisely by the transformation products of coffee compounds circulating in the blood.

The method of preparation also affects the intensity of the benefits: the degree of roasting, the type of grinding, and filtration change the concentrations of active substances and their bioavailability. Scientists emphasize that the effect of coffee significantly depends on individual factors - genetics and the composition of the gut microbiota, which determine how the body processes the compounds in the drink.